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"CRISPR" and "Cas9" are different things. When a virus attacks a bacteria, the bacteria stores the viral code of the virus in CRISPR. And when the virus attacks again the Cas9 protein uses the RNA in the CRISPR to find the viral DNA and then destroy it.

So, what is the use of CRISPR when scientists use the CRISPR/Cas9 system to edit genes, as we have already given the Cas9 protein a guide RNA?

Sorry if this is a stupid question, I am new to genetic engineering and couldn't find the answer on google.

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  • $\begingroup$ I might be wrong here. But, when a virus attacks a bacteria, the bacteria stores the viral code of the virus in SPACERS and not CRISPR. 'Spacers' refer to the segments of DNA between the CRISPR. $\endgroup$
    – skpro19
    May 18 at 15:41

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