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The electrochemical gradient of Na+, K+, Ca2+, and Cl- between the inside and outside of a neuron is vital for its function. When a neuron fires, this gradient reverses. How long does it take for the gradient to be re-established?

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    $\begingroup$ Does this answer your question?: biology.stackexchange.com/q/57064/27148 Gradients don't reverse during an action potential, only permeabilities chance substantially. Yes, a few ions do move and pumps are needed to restore concentrations, but it's very few ions. $\endgroup$
    – Bryan Krause
    Commented Jun 11, 2021 at 14:12
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    $\begingroup$ Also biology.stackexchange.com/a/76167/27148 $\endgroup$
    – Bryan Krause
    Commented Jun 11, 2021 at 14:14
  • $\begingroup$ Thanks for the clarification. Although I knew the voltage change, I didn't realize how few ions are actually needed to cause that change. If you post an answer saying the same thing I'll pick it as correct. $\endgroup$
    – E Tam
    Commented Jun 11, 2021 at 18:05

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