I’m trying to figure out how to use Alphafold, which is a biological analysis software for predicting the folding of amino acid sequences. I’ve been trying to follow the directions on the creators’ website for downloading it and using it but there’s one part I don’t understand (see the sections mentioned in the link below), and because a mistake here could be costly, I would like to understand it before I make a mistake. To me, the website seems to be saying that I have to download the software, and then also download the two terabytes worth of data that the model was trained on, and that having both the sotware and the training data will allow me to predict the folding of new amino acid sequences (kind of like if I’d have to train the model myself). This seems odd to me because although I don’t know much about modelling software, it was my understanding that the software creators use data to train a model, find what model would best predict new inputs, and then give you that pre-set model.
My question - do I have to download both the Alphafold model and all that data in order use the software to predict the folding of new amino acid sequences? In particular, if I really only just want a visualization of the folding and accompanying statistics, is this the simplest way for someone with little background in programming (although my university does have the storage capacity for the data if need be)?
(See the Model Parameters and Running Alphafold sections of this github link: https://github.com/deepmind/alphafold)