So, I would like to ask, why don't we use just DNA hybridization instead of PCR primer amplification to diagnise some illness?
I know, when you have a really small amount of DNA from virus or cell you need to amplifie it, so you can do some hybridizations. But I cannot find out, why you need to amplifie it when you have like 10 ml of substance, where the amount of cells or viruses can be really high.
For instance, when you are trying to diagnose some chromosomal aberation you don't amplifie the DNA, so you do just hybridization, but when you are trying to detect coronavirus you use PCR, why?
I have all the information from Genetics by Eduard Kočárek (Scientina 2008) - so now you know the literature my question is based on.