What were the criteria devised for the numbering convention employed in human chromosomes? When was it fixed?
Correct me if I am wrong; it appears that chromosome pairs 1 to 22 were originally ordered in terms of perceived structural size, which ended up fitting neatly with the quantity of base pairs (but not with the quantity of genes).
The sex chromosomes in turn were arbitrarily assigned as "pair 23".
Is this sound?
Thanks in advance.