It is estimated that soon after the "out of Africa event" there was some interbreeding between Homo sapiens sapiens and Homo neanderthalensis. All non-African peoples are thought to have around $2\%$ of their DNA from Neanderthals due to this cross-breeding event.

Can it be estimated how much of the genetic difference/distance between Africans and non-Africans is due to this mixing event?

  • 2
    $\begingroup$ @bob1 If you take two populations identical in allele frequency and crossbreed one of those with Neanderthals you would initially expect close to 100% of the difference to be due to the crossbreeding event. $\endgroup$
    – Agerhell
    Jun 3 at 23:00
  • $\begingroup$ Yes, indeed. However, how many generations since the cross-over event between us and Neanderthal, and what is the genetic difference now? $\endgroup$
    – bob1
    Jun 4 at 22:06
  • $\begingroup$ Multiple cross-over events are thought to have occurred, (possibly more in some populations than others, not sure). $\endgroup$ Jun 4 at 23:55
  • 1
    $\begingroup$ @JiminyCricket for Neanderthals? I think only a single admixture (not cross-over, that’s recombination) event occurred. You may be thinking of multiple admixture events with Denisovans. $\endgroup$
    – user438383
    Jun 6 at 8:05
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    $\begingroup$ Why don't you compose an answer @envs_h_gang_5, you seem to have the basis of one there. $\endgroup$ Jun 11 at 3:05


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