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I have been told that DnaA binds strongly to DnaA boxes on the E coli genome, but binds weakly to 8 out of 11 sites near ori. I want to know more quantitatively what strongly and weekly mean. Are there order of magnitude estimates of binding energies of DnaA to various locations on the E. coli genome?

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    $\begingroup$ I would suggest searching the literature for answers, I didn't instantly find binding energies but I could readily find dissociation constant estimates. $\endgroup$ Jun 20, 2023 at 17:23
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    $\begingroup$ @MaximilianPress Thank you, this is helpful. I had done a quick search and hadn't found anything, but I wasn't searching for dissociation constants, which is equally useful. Feel free to post this as an answer, and I will accept it. $\endgroup$
    – stochastic
    Jun 21, 2023 at 12:15

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