I know that in E. coli the lactose operon is shut down by CAP protein when binding cAMP. Is this true also for Gram positive bacteria?


1 Answer 1


I know it's stupid but I answer my own question, for those who are interested. It is different. CAP protein regulates lactose operon only in Gram -. In Gram + the presence of glucose shuts down the operon with another mechanism: the TCRS that relies to concentration of fructose 1,6 phosphate.

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    $\begingroup$ It is not stupid to answer your own question! It is actually encouraged on every SE site :) $\endgroup$
    – biogirl
    Feb 19, 2014 at 12:21
  • $\begingroup$ Its not stupid at all. You saved our time $\endgroup$ Jun 12, 2016 at 1:38

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