I am thinking how CVC in lungs lead to the left-sided heart failure.
I think CVC lead to Pulmonary congestion and edema. They produce heavy, wet lungs.
Pulmonary changes include
- perivascular and interstitial edema, particularly in the interlobular septa;
- progessive edematous widening of alveolar septa; and
- accumulation of edema fluid in alveolar spaces which contain Hemosiderin and microhemorrhages
Now, the progression of the disease to heart should be discussed. I am not sure if hemosiderin can go directly from lungs to heart or if it has to travel through circulation and then to left-side of lung.