After thinking about it, I'm confused by what the reaction barrier of an enzyme actually means.
Imagine a reactor containing enzyme and substrate.
If the enzyme in the reactor has a reaction barrier of 15 kcal/mol,
a) then when 1 mole of product has formed, that means 15 kcal have been consumed, independent of how much enzyme is present in the reactor.
b) then when 1 mole of enzyme is present in the reactor and 1 mole of product is formed, 15 kcal have been consumed.
Is it option a), b) or otherwise?
Let us imagine two companies A and B. Both companies use very similar technical equipment to carry out a biotechnological process where a chemical reaction is catalyzed by an enzyme. Company A uses an enzyme with a reaction barrier of, say, 15 kcal/mol, while company B uses an enzyme to catalyze the same reaction but this enzyme has an activation energy of only, say 12 kcal/mol. For every Mole of product, company B saves 3 kcal worth of energy needed to drive the factory.
Does that make sense?