How is the rate of transcription influenced by temperature? More precisely, I am looking for an article who quantitatively measured the rate of transcription of an "average gene" and show how this rate is influenced by temperature.

On this question @Chris found this article where such measurement were performed but they were using some arbitrary unit (as it as been pointed out by @shigeta here) that cannot be related to any comprehensive unit such as "mole of amino acid per hours" or something like that.


1 Answer 1


If your looking at transcription then your talking about RNA POLYMERASE.

And there are many variants. Here's a good Nature paper that discusses temperature and RNA Pol


And another:


I couldn't get full access to this JBC paper but I think the answer would be clearly in here, prob worth a look

M. Chamberlin and J. Ring. Characterization of T7-specific ribonucleic acid polymerase. 1. General properties of the enzymatic reaction and the template specificity of the enzyme. J Biol Chem. 248: 2235-44 (1973)

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    $\begingroup$ Very nice. Thanks a lot. I found the answers I needed in the Chamberlin and Ring article. There's a similar question here if you feel you can answer it $\ddot \smile$ $\endgroup$
    – Remi.b
    Sep 11, 2014 at 20:37

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