My professor says that some drugs cannot be used with grapefruit. I am trying to search a list of cytochromes and their effect to block members in the cytochrome family. Some in Cyt P450.

What is the main meta-analysis of fruits in blocking cytochrome family?


1 Answer 1


While I haven't found a list which is restricted to fruits, I found this page: P450 Drug interaction table. They list quite a number of substances which inhibit different isoforms of the P450 protein and also give the original references.

This list gives a large number of herbals which inhibit different P450 isoenzymes. The disadvantage is that they do not give further references so if you want to have a closer look you will probably have to spend some time with Pubmed.

  • $\begingroup$ Thank you! The table includes the grapefruit juice as moderate inhibitor that was emphasized by my lecturer. I did not see any other significant food there. $\endgroup$ Sep 17, 2014 at 13:31
  • $\begingroup$ The second list contains a number of latin names of different plants. If you translate them into the normally used ones (Wikipedia is helpful here) you can see if there are other fruits among them. $\endgroup$
    – Chris
    Sep 17, 2014 at 13:47
  • $\begingroup$ I asked my old Latin teacher how to learn the latin names of different fruit. I think there is some logic behind the fruit names. $\endgroup$ Sep 17, 2014 at 18:39
  • $\begingroup$ Add the complete latin name into the search field of the Wikipedia to get the normally used name. Works pretty well. $\endgroup$
    – Chris
    Sep 17, 2014 at 18:44
  • $\begingroup$ Any possibility of doing it for those all at once? Doing list search? $\endgroup$ Sep 17, 2014 at 19:56

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