I claim that one great limitation in our understanding of the healing process is that biologists have no understanding of the progression of disease or infection, that not enough time may be given for the body to recover, and that doctors might not understand how to help their patients recover from disease or infection.
Each patient is different, and personalised recovering plan is often important.
So, too few resources — e. g.: the time of a doctor and/or a nurse — are offered to patients, so doctors have little time to build their understanding of the disease or injury with which their patients are dealing.
It is the patient who makes himself or herself able to recover.
But, without understanding, the recovery process is not optimal.
Healing from upper respiratory infection:
I will give one example in LOR Medicine.
Upper respiratory infections are one of the most common infections and most expensive diseases in society.
One reason is that people do not understand:
- how to recover from disease
- how long the common cold or flu lasts (doctors underestimate the time that it will take for their patients to heal very often.)
In nursing school, they teach students how to, among other things:
There is no way to measure what the correct course of treatment is for any given patient during the course of, for example, an upper respiratory infection.
Nurses ask the patient when he or she feels their best and adjusts treatment accordingly.
So, good communication is essential in nursing.
Chris and Cornelius cover some of the basic cellular processes of wound healing.
However, some big steps are still missing in regards to healing.
The primary healing of wounds is aided by:
- adequate wound-edge coaptation
- healing without complications
- minimal scar tissue
through the cellular processes of wound healing described by Cornelius and Chris.
Secondary healing of wounds is characterized by:
- wound tissue left exposed (open)
- defect filled with granulation tissue
- surface covering the epithelium
- less functionality
- possible thermal and mechanical injuries
Embryological and biochemical aspects of tissue healing
I cover here some growth factors.
If they are not present, then their absence will surely be a limitation to the healing process.
- TGF - transforming growth factor
- MDGF - macrophage-derived growth factor
- HB-ECG - heparin-binding epidermal growth factor
Here are some other factors:
- bFGF - basic fibroblast growth factor
- KAF - keratinocyte-derived growth factor
Special cytokines for inflammation may later come into play.
- Human skin wounds: a major and snowballing threat to public health and the economy. Sen C.K., Gordillo G.M., Roy S., Kirsner R., Lambert L., Hunt T.K., Gottrup F., Gurtner G.C., Longaker M/T. Wound Repair Regen. 2009 NovDec;17(6):763-71.
- My notes during 4 years of nursing
- My notes during classes of Surgery
- My notes of Embryology and Surgery about the growth factors