The whole question is
What is the optimal frame size for the second and third generation protein secondary structure prediction methods? Justify your answer.
I remember it has something to do with the average length of alpha-helix. More specifically, 3 on both side of a site. So in total the frame length should be 7. But I can't remember the reason behind the argument.
What do you think?
According to what my professor said in class, 2nd and 3rd generation of protein secondary structure reconstruction relies on statistics data of several consecutive residues. I guess what he meant by "frame size", is how many adjacent residues we should take into account in the algorithm.