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Benign tumors can grow to dangerous size yet are they capable of metastisizing ; if not what stops this? Also with a benign tumor if you call its cells 'near' its edges its tumor 'cell wall' I was wondering if the cells in its Tumor Cell Wall still have apoptosis mechanisms in them that function?

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  • $\begingroup$ If tumors metastasize, they are not benign. $\endgroup$ Commented Oct 18, 2014 at 6:10
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    $\begingroup$ Afaik they still have apoptosis, but they slowly develop a resistance to signals which can trigger it. That's why they need stronger signals to stop proliferating than normal cells . $\endgroup$
    – inf3rno
    Commented Oct 18, 2014 at 12:53
  • $\begingroup$ How do benign tumors develop a resistance to signals that can trigger apoptosis? If a benign tumor has stopped growing would this mean it has some active apoptosis mechanisms? $\endgroup$
    – user128932
    Commented Oct 20, 2014 at 5:49

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