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I'm looking for suggestions of the mechanistic level at which genotype*sex interactions can occur. These give different phenotypes from the same genotype dependent on the sex they are expressed in. For example, cis-acting sex-specific modifiers can affect gene expression.

What other mechanisms can create a gene*sex interaction?

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  • $\begingroup$ I am a little unclear about what you mean by gene*sex interaction $\endgroup$ – WYSIWYG Mar 2 '15 at 8:26
  • $\begingroup$ genotype*sex interaction in determining the phenotype, so a single allele could produce different phenotypes depending on which sex it is in, I am trying to find some known examples of how these sorts of things occur (e.g. known sex-specific gene expression regulation pathways) @WYSIWYG $\endgroup$ – rg255 Mar 2 '15 at 10:35
  • $\begingroup$ Something like this and this ? $\endgroup$ – WYSIWYG Mar 2 '15 at 11:03
  • $\begingroup$ Are you talking about genomic imprinting? $\endgroup$ – cagliari2005 Mar 29 '15 at 17:08
  • $\begingroup$ So you want to know about the specific molecular mechanisms (e.g. interactions between gene products), and not just examples of gene*sex interactions? $\endgroup$ – fileunderwater Mar 29 '15 at 18:30