In a previous post of mine, I asked how to supress the creation of anti-antibodies in vivo. In the answer, it was mentioned that site-directed mutagenesis could be used. Currently, I can't find mcuh on how to do so... How does this work?

Update: As people want to know where this idea is coming from, here is the link to my previous question about it.. look in the answer for more info:

How to inhibit formation of specific antibodies (to antisera)?

  • $\begingroup$ Could you link to your previous post for context? Site-directed mutagenesis is nearly impossible to perform in vivo, so I'm wondering what the comment poster was getting at... $\endgroup$
    – MattDMo
    Dec 12 '14 at 21:51
  • $\begingroup$ You want to do site-directed mutagenesis in unspecified living cells in a living body? How do you want to select the cells which make the auto-antibody? This will never work. $\endgroup$
    – Chris
    Dec 12 '14 at 21:53
  • $\begingroup$ @Chris it was just a comment provided by the answer for my previous question.. I will give you the link $\endgroup$
    – TanMath
    Dec 12 '14 at 21:59

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