Oxygen is transferred by hemoglobin from the lungs to tissues, while carbon dioxide is transferred by hemoglobin from tissues to lungs. How is this regulated bidirectional transfer mediated?


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Under conditions of high CO2 (in tissues such as muscle) and hence high acidity hemoglobin binds preferentially CO2, thereby mediating CO2 removal. Under conditions of low CO2 (high pH) and high O2 (conditions met in the lungs), it preferably binds O2, thereby releasing CO2. Hence, the specific characteristics of hemoglobin allow for CO2 uptake in the body, and O2 uptake and CO2 release in the lungs. Info from wikipedia on hemoglobin

  • $\begingroup$ please explain more.and the primary purpose is mechanism of exchanging O2 and CO2.mostly from biochemistry pointview. $\endgroup$ – user12874 Jan 10 '15 at 15:04
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    $\begingroup$ @Majid have you done any research on your own? Did you read the Wikipedia article and those linked to it? Your questions are quite broad. $\endgroup$ – MattDMo Jan 10 '15 at 23:34