The options provided are-
- Chronic blood loss
- Sickle cell anaemia
- Haemolytic anaemia
- Transfusion reactions -
*Q-15: pg-785; **Review of Medical Physiology - William F. Ganong; International 22nd Edition***
Here, the answer provided is (4), i.e Thallasaemia... My point is that, Thallasaemia is essentially a genetic defect resulting in mutation of either alpha or beta or both the chains, thus rendering the structure of haemoglobin fragile....the disease as far as I know don't cause any reduction in blood volume...
According to me option (1) i.e chronic blood loss is more feasible as in case of diseases resulting from nematodes like Hookworm (Ancylostoma duodenale)....
So, where am I wrong???