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The classical definition of the Genetic Matrix

G = ZZ'/2p(1-p)

where Z = M - P

where P = 2(p-0.5)

I don't have a background in biology but understand Maths and Computer Science very well. I am trying to wrap my head around

1) Why do we define P the way we do? 2) Why do we subtract P from M 3) How to interpret a negative entry in G? 4) Does the j,k element of G give me the genetic distance between j and k individuals?

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    $\begingroup$ Welcome to Biology.SE. What is P? what is M? What is this genetic matrix suppose to represent? Is it a matrix of genetic variance and covariance for $n$ traits? Can you link to where you found those things? $\endgroup$ – Remi.b Apr 16 '15 at 20:26
  • $\begingroup$ Sure, here it is. nce.ads.uga.edu/wiki/lib/exe/… $\endgroup$ – ganesh reddy Apr 16 '15 at 20:34
  • $\begingroup$ Any clarifications you could provide would be much appreciated. $\endgroup$ – ganesh reddy Apr 16 '15 at 20:36

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