The classical definition of the Genetic Matrix
G = ZZ'/2p(1-p)
where Z = M - P
where P = 2(p-0.5)
I don't have a background in biology but understand Maths and Computer Science very well. I am trying to wrap my head around
1) Why do we define P the way we do? 2) Why do we subtract P from M 3) How to interpret a negative entry in G? 4) Does the j,k element of G give me the genetic distance between j and k individuals?