I was jogging when I asked myself this question:
In running contests the standard running direction is counterclockwise; I also believe to remember that the regulation is very old (right back to the Greeks and Romans). I suppose the reason is that most people have a stronger dominant right leg and running counterclockwise feels more natural.
Now there are people who are "left-legged": They have a stronger and dominant left leg. What I ask is: How would the times change overall if we revert the direction and let the runners run clockwise ? Has someone experimented with it ? Is the effect discernible or even decisive ? Would left-legged people get an advantage ?