I have to analyse two datasets consisting of time-series measurements of gene expression. One set are in vivo data from the expression profiles obtained between a few days before birth to several days post-partum. The second data set was obtained in a C2C12 cell line, where t = 0 was defined as the day in which 100% confluence was reached.
Is there an optimal way to align the two time series? Simply aligning the two series using the two t= 0 samples as starting point seems arbitrary.