I've read from an academic article that diamine oxidase cannot be supplemented but it had no explanation as for why. I am curious as to why this?
Food rich in histamine or red wine may cause allergy‐like symptoms such as sneezing, flush, skin itching, diarrhoea and even shortness of breath. The suspected reason is a diminished histamine degradation based on a deficiency of diamine oxidase. As diamine oxidase cannot be supplemented, a histamine‐free diet was implemented to reduce histamine intake.