What is the correct meaning of cytogenetic notation "inv(4)(p13q22)" ?

  1. Inversions at chromosome 4, at the p arm 13 is inverted AND at q arm 22 is inverted


  1. Inversions at chromosome 4, the p13 is Swapped with q22
  • $\begingroup$ Do you have a source $\endgroup$ – rg255 Aug 18 '15 at 19:18

Those are the break points of the inversion. So chromosome 4 was cut at p13 and q22 and the fragment was reinserted in the reverse direction, giving a pericentric inversion.

  • $\begingroup$ So the explanation number 1 is the correct !!!! $\endgroup$ – d.putto Aug 18 '15 at 11:50
  • $\begingroup$ @d.putto Actually neither really sound correct to me. $\endgroup$ – canadianer Aug 18 '15 at 17:12

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