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I am somewhat of a newbie in evolutionary biology currently taking my first steps in bioinformatics. I was reading a paper when I came across the term "constrained genetic elements", referring to sequences in the genome.

From what little I found googling the term, a constrained genetic element is a sequence/region in the genome that can be found preserved in many generations of a species. Is my understanding correct? What are the criteria by which those regions are identified?

The paper is Analysis and Classification of Constrained DNA Elements with N-gram Graphs and Genomic Signatures.

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    $\begingroup$ In what paper did you find the term? And in what context in the paper? $\endgroup$ – kmm Sep 17 '15 at 15:24
  • $\begingroup$ @kmm I added the paper title. The term is mentioned when explaining that classification is applied to "conserved sequences" in the genome, but no further explanation is given. $\endgroup$ – VHarisop Sep 17 '15 at 15:28

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