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Is HLA matching/ blood grouping required for corneal transplants ? I think,it shouldn't be, because cornea is avascular.

I tried searching on the net but most of the references are old and controversial. So please provide a reliable and latest reference for your answer.

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    $\begingroup$ Just because it's avascular doesn't mean immune cells can't/don't infiltrate. There are plenty of inflammatory eye processes where the cornea and lens can be targeted. $\endgroup$
    – MattDMo
    Commented Oct 5, 2015 at 17:27

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Cornea is considered as an "immune-privileged" site and tissue, neither HLA nor blood grouping is required for allogeneic corneal transplant.

In terms of reference: This could be one: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2802514/

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