My question maybe very primary, but after I learned this part, questions always follow me. SDS-PAGE gel works for detect protein, agarose gel works for detect nucleic acid, so here is my question: 1. Why does SDS-PAGE works for protein, and agarose gel works for nucleic acid? Is it any possible to use SDS-PAGE to detect DNA? Or use agarose to detect protein?
Why does the SDS-PAGE gel always runs vertically, and agarose gel runs horizontally? Are they necessary?
Is any other material could be use in gel electrophoresis?