The question title says it all. What happens in my brain when I resist sleep? I would appreciate explanations on neurotransmitter changes, what areas of the brain activate to resist sleep, what can an EEG tell us about that condition, are there any phases to that condition..

Switching to sleep mode is very complex and automatic process and it takes over and changes the functions of the whole brain (and the whole body also), so..

What actually does the brain do to not fall asleep?


One of the things that can happens when you don't sleep is that you keep producing a lot of waste without maintenance.

Philosophically speaking, you also have your free-will in this role. some conditions are your strength, your motivation, your control, maybe your instinct some times. However in the end you are a conscious about taking the control of your material self, how to do and when.

So except the DMT that its released by your body, probably by the pineal gland after some days without sleeping (I don't find a reference), I believe its mostly the same areas active but over exhausted.

Here are some useful links:



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    $\begingroup$ This doesn't answer the question. $\endgroup$ – Dexter Nov 10 '15 at 9:03
  • $\begingroup$ i dont agree with these correction. one of the things that happens, because its a fact . its nothing hard to know if its not cleaning, if your are over using you are over acumulating the waste. then Conscient Being.like human being .. and now i wanna know why this answer the question? its not a complete answer, but it says a lot about "what happens" and what the bain do, $\endgroup$ – Barreto Freekhealer Nov 10 '15 at 13:28
  • $\begingroup$ OP is asking about how the brain resists sleep, not what the results would be. $\endgroup$ – jzx Feb 4 '16 at 17:30

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