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What is the germ layer origin of human lung-derived fibroblasts?

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All normal fibroblasts are mesenchymal in origin, including lung fibroblasts. In certain situations, usually injury related, epithelial cells can undergo an epithelial to mesenchymal transition (EMT).

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  • $\begingroup$ Even dermal fibroblasts? $\endgroup$ – user391339 Nov 13 '15 at 1:24
  • $\begingroup$ Yes, all fibroblasts with the exception I listed in my answer. $\endgroup$ – akaDrHouse Nov 13 '15 at 1:26
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The table at http://genome-mirror.duhs.duke.edu/ENCODE/cellTypes.html lists many commercially available cell lines. The four lung fibroblast lines, including adult and fetal, are listed as endodermal in origin.

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