Is it just that a BAC is generally larger and artificially constructed? Or are there any other differences?


BACs are a special kind of plasmid, based on E. coli's F-plasmid:

The BAC is based on a plasmid in Escherichia coli that is termed the F (for fertility) plasmid. The F plasmid (or F factor) contains information that makes possible the process called conjugation . In conjugation, two Escherichia coli bacteria can physically connect and an exchange of DNA can occur.

A BAC contains the conjugation promoting genetic information as well as stretch of DNA that is destined for incorporation into the bacterium.


It isn't necessarily larger than a plasmid.


Your Answer

By clicking “Post Your Answer”, you agree to our terms of service, privacy policy and cookie policy

Not the answer you're looking for? Browse other questions tagged or ask your own question.