1. In mitosis am I correct in saying that the spindles attach to the centromeres at the end of prophase/prometaphase? (I read this in an answer to another question)


  1. Does the nuclear envelope disintegrate during prophase (as occurs in mitosis), or during metaphase? (this is what it says on my textbook)

  2. When do the spindles attach to the chromosomes during the first phase? (during prophase I, or anaphase I? On my textbook it says anaphase I)

  3. And when do they attach to the sister chromatids in phase II? (on my textbook it says metaphase II).


closed as unclear what you're asking by AMR, MattDMo, AliceD, March Ho, fileunderwater Jan 14 '16 at 9:35

Please clarify your specific problem or add additional details to highlight exactly what you need. As it's currently written, it’s hard to tell exactly what you're asking. See the How to Ask page for help clarifying this question. If this question can be reworded to fit the rules in the help center, please edit the question.

  • $\begingroup$ Why would you doubt the answers you are reading in your textbook? It should be accurate, at least for a phenomena as well characterized as Mitosis and Meiosis. $\endgroup$ – AMR Jan 10 '16 at 20:45
  • $\begingroup$ Please limit yourself to one question per post. $\endgroup$ – MattDMo Jan 10 '16 at 21:08
  • 1
    $\begingroup$ Is there some reason that you doubt the textbook? $\endgroup$ – rg255 Jan 11 '16 at 12:06
  • $\begingroup$ @rg255 I doubt the textbook because other reliable sources were giving contradicting information, and my teacher even mentioned that in some parts it was not specific/accurate enough. $\endgroup$ – city7lights Jan 14 '16 at 1:02
  • $\begingroup$ Then you should give the sources for the both sides of the contradictory information $\endgroup$ – rg255 Jan 14 '16 at 6:47

Mitosis: 1. Yes, the spindle fibers attach to centromeres at the prometaphase


Meiosis: 1. The nuclear membrane breaks down in Metaphase 1 and reforms during Telophase. It breaks down again in Prophase 2, reforming after that in Telophase 2 in the daughter cells.

  1. The spindles attach to the centromere is Metaphase 1

  2. Yes the spindles attach to the sister chromatids in Metaphase 2

Check out this animation, it might be pretty useful


Not the answer you're looking for? Browse other questions tagged or ask your own question.