I've read that during mitosis, DNA exists as heterochromatin, a form that is unable to be accessed for transcription.

Does this mean no new proteins are made during what can be 20% of a cell's life? How does the cell survive?

  • $\begingroup$ To make proteins you just need mRNAs. And most of the synthesis (transcription) is done in the S-phase, including the mRNAs required for later stages. $\endgroup$ – WYSIWYG Jan 18 '16 at 14:12
  • $\begingroup$ Consider two values, the average half-life of an mRNA, and the average half-life of a protein. A cell may not need to transcribe it's essential genes non-stop. $\endgroup$ – mdperry Jan 19 '16 at 3:09

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