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What is the oxygen carrying capacity of immature red blood cells, or reticulocytes? Is there any difference between oxygen carrying capacity of mature and immature red blood cells?

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This was studied by Steve Fishbone et al and concluded that the Hb content of a Reticulocyte is slightly higher than that of a mature RBC. The CHr, which is the Hb content of a reticulocyte in CRF patients receiving Erythropoetin is around 27.5 +/- 2.5 pg

Ref: Fishbone S, et al. Reticulocyte Hemoglobin Content in the Evaluation of Iron Status of Hemodialysis Patients. Kid. Int., 1997; 52: 217-222

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  • $\begingroup$ Interesting. Is this the Hb content per cell? Is it considered a normal value? $\endgroup$ – Roland Mar 5 '16 at 21:20
  • $\begingroup$ Hi Roland! Thats the value in CRF patients! It could be slightly lesser by about 5-10% in normal individuals $\endgroup$ – user118008 Mar 8 '16 at 0:49

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