Trypsin is secreted in the small intestine to convert proteins into dipeptides i.e. to carry out digestion of proteins. However, it is also a coagulating agent which coagulates blood by hydrolysing fibrinogen into fibrin. My question is, why doesn't the blood in the small intestine coagulate?

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    $\begingroup$ Remember trypsin is an intraluminal enzyme, and is not normally in contact with blood. $\endgroup$ – Maljam Mar 12 '16 at 5:09

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