I find listed on the Sigma-Aldrich site a large list of enzymes & corresponding inhibitors. e.g. For the enzyme squalene synthase the inhibitor listed is "Zaragozic acid A trisodium salt"
Would this mean that if I added the right amount of this chemical to, say, a Yeast cell culture I might expect to get reduced activity of Squalene Synthase which is native to yeast and catalyses the transformation of FPP to Squalenes.
Would this even be a reasonable thing to try if I had a goal to block Squalene synthase? Or am I interpreting how these inhibitors ought to be used incorrectly? Can they be used with in vivo cultures at all?