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I found out that the number of $Na^+$ ions that is needed to be transfered across the membrane to make it depolarized is a small number. In what way its proved? (Goldman equation maybe?)

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  • $\begingroup$ You mean how the exact number of ions passing the membrane is measured? $\endgroup$ – Chris Apr 5 '16 at 18:15
  • $\begingroup$ One ion is enough to depolarize it. It depends on how much depolarization you are looking for and on the areal surface you want to depolarize and on the exact physiological ionic composition in and out of the cell at that time $\endgroup$ – AliceD Apr 11 '16 at 9:50

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