I see that aspirin (in part) works by inhibiting cycloxygenase isoenzymes and that this inhibiting is irreversible. I've had a few classes mentioning this topic in passing, but never with depth.
I guess my question regards the permanence of the word "irreversible." I assume enzymes have a life span, so to speak, and that the same isoenzymes both die and are being replenished at some given rate.
Am I correct in thinking that the cycloxygenase enzyme is permanently inhibited until its death (catabolism)?