For an upcoming experiment I would have two kinds of DNA fragments in a sample after a particular reaction step: First there would be fragments of a length of approx. 170 bps and then there would be Fragments of a length of approx. 270 bps or more.
I would like to maintain all fragments with a length of 270 bps or more and throw out all fragments with a length of 170 bps.
Of course, I could run everything on a gel and collect just those bands above 170 bps. However, I am wondering whether there is something more elegant to reach that aim. For instance, we could use a filter that collects just those fragments with a size of 200 or 250 bps or more and those fragments with a smaller size flow through the filter. Is such a thing possible and if so, how? Or would you suggest something else?
Many thanks for your support in advance!