I am in the process of a OCR GCSE Case Study, and my question is "Do the benefits of anabolic steroids outweigh the risks, which has an obvious conclusion. I need to know the scientific name, or a scientific analysis of why it causes an increase in protein synthesis, for the binding of cortisol to understand this quote:"Anabolic steroids may block the binding of cortisol to its receptor sites, which would prevent muscle breakdown and enhances recovery.". For without enough understanding i can't explain it.
The intracellular receptor for cortisol is called NR3C1. http://www.uniprot.org/uniprot/P04150
To my knowledge, a direct (competitive) effect of anabolic steroids on the binding of cortisol to NR3C1 has never been proven. The anabolic effects can easily be explained by other targets. A good starting point for further reading might be this review: https://www.ncbi.nlm.nih.gov/pubmed/22101547