In my VCF file from GATK, I have the following definitions for
AD - Allelic depths for the ref and alt alleles in the order listed DP - Approximate read depth (reads with MQ=255 or with bad mates are filtered
I don't understand the definitions, can anybody explain in a less technical way?
From what I can read,
AD gives the number of reads spanning the reference and variant allele. But what does
DP mean? This doesn't look like the total number of reads spanning a variant, so what is this? How does this different to