Recently an interesting study has reported. Zhou et al., 2016. J. Cell Biol. http://dx.doi.org/10...3/jcb.201605101
According to this study, enhancing anterograde axon transport of mitochondria is essential for regeneration of injured axons.
Neurons need a large amount of energy provided by ATP to extend their axons when they are injured. Mitochondria transported to axons produces ATP which is necessary for that.
This study shows that in mature neurons, the motility of mitochondria is reduced and the reduced mitochondrial motility might be the cause of the deficit in regrowth capacity of mature neurons. Moreover, this study found that enhancing mitochondria transport enables mature neurons to recover their regrowth capacity.
It is said that mature neurons typically arrest their cell cycle and fail to proliferate and regrow. However, considering the fact that only enhancing mitochondria transport enables mature neuron to recover their regrowth capacity, I can't help but doubt the commonly accepted theory.
Do mature neurons actually not arrest their cell cycle？
What do you think of this finding ？