So, I have calculated the frequency of all SNPs (single nucleotide mutations) in some samples and have also found the nucleotides on the 3' and 5' sides of the mutated nucleotide. So I have a list of 192 possible permutations like this one:
AAA -> ACA 43 AAA -> AGA 35 AAA -> AAA 134 . . TGA -> TAA 345 TGA -> TCA 25 TGA -> TTA 97 . .
What is the statistical approach to show that a particular set of 4 of these mutations is significant?
I have little knowledge in statistics so I welcome a for-dummies explanation!