The class of 5-HT1 receptors binds serotonin (5-HT) reversibly (Wikipedia). I'm interested in the on-rate and off-rate constants $k_{\text{on}}$ and $k_{\text{off}}$ of this process.

So my question is: Have these constants already been determined experimentally for any member of the 5-HT1 receptor family, and, if so, what where the values observed?

Edit: Since this question didn't get much attention yet: Instead of the on-rate and off-rate, maybe the dissociaton constant/binding constant of the binding process is known?


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