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Here is an imaginary mRNA sequence: 5’- THE BIG BOY SAW THE CAT EAT THE HOT DOG – 3’ Each 3 letter-word is equivalent to the codons in real mRNA.

What would the imaginary mRNA sequence look like if there was a deletion of two bases near the 5’ end of the mRNA? Write out the example above with the two-base deletion and 3-letter “codons” to explain your answer. Label the ends of your imaginary RNA and clearly show the mutation.

I used this: 5’- TBI GBO YSA WTH ECA TEA TTH EHO TDO G-3’. However I am not sure if writing in this form answers the question, can someone tell me whether this is correct and if not how should I change it?

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No your answer seems correct, but are you sure they aren't asking you to delete the two bases at the absolute 5' end? In that case it becomes:

5’- EBI GBO YSA WTH ECA TEA TTH EHO TDO G – 3’

But if they're asking you to delete any two near the end, then you're correct.

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  • $\begingroup$ Okay, is it necessary to put ... at the end of the 3' end for this question? $\endgroup$
    – user27905
    Nov 20, 2016 at 21:26
  • $\begingroup$ I don't understand, I haven't put three dots? It's just G – 3’ $\endgroup$
    – Malhar Khushu
    Nov 21, 2016 at 3:07
  • $\begingroup$ Yeah, that shows that the mRNA is going from 5' to 3' and that it's ending there $\endgroup$
    – Malhar Khushu
    Nov 24, 2016 at 3:09

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