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I have recently read in a book that organelles like ER (endoplasmic reticulum) and Golgi Complex cannot be seen under a compound microscope during cell division. Why does this happen, and where do the organelles go during that time?

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    $\begingroup$ Could you cite which book you read this in? $\endgroup$ Commented Dec 29, 2016 at 18:44
  • $\begingroup$ In my textbook of 11 th grade. $\endgroup$
    – jyoti proy
    Commented Dec 29, 2016 at 18:45
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    $\begingroup$ By saying "disappear" I actually mean - cannot be seen under compound microscope, as under normal circumstances ER can be clearly seen. $\endgroup$
    – jyoti proy
    Commented Dec 29, 2016 at 18:49
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    $\begingroup$ Please include the title, year published, editors, edition, and publisher of any cited works if possible. $\endgroup$ Commented Dec 29, 2016 at 18:49
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    $\begingroup$ This is not my area of expertise at all, but here are some recent papers that might shed light on this: journals.plos.org/plosone/article?id=10.1371/…, ncbi.nlm.nih.gov/pmc/articles/PMC2719565, jcb.rupress.org/content/179/5/895 $\endgroup$
    – Gaurav
    Commented Dec 30, 2016 at 23:58

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A cell when undergoes the process of cell division there are structures known as spindle fibres that are required to pull the chromosomes off to the poles of the cell so that it can be segregated into the cells properly while division. These spindle fibres are made of microtubules that are protein molecules constituting the cytoskeleton of a cell. Endoplasmic reticulum and Golgi apparatus are also providing a lot of support to the cells. Also endoplasmic reticulum and Golgi apparatus are the sites where most of protein forms. While cell division these two organelles disintegrate so as to provide protein for microtubules formation, and so as to reduce support of the cell so the division of the cell is comparatively easier. Also, during the cell division everything divides equally between the two daughter cells, so ER and Golgi bodies disintegrate so they can be equally divided into the two daughter cells. Also, nuclear envelope is the continuation of the endoplasmic reticulum. Hence endoplasmic reticulum disintegrates with the nuclear envelope.

Here I have provided a set of possible reasons for your question.

You can refer Raven's biology for further information.

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  • $\begingroup$ Could you please provide citations of your claims, which would help to enrich the answer. Also I don't get the point "While cell division these two organelles disintegrate so as to provide protein for microtubules formation" which you have said, as all the proteins required to run the division phase of the cell cycle are synthesized during the G1 phase so there is no need to disintegrate some organelles to provide that. $\endgroup$
    – jyoti proy
    Commented Feb 13, 2017 at 19:18
  • $\begingroup$ ncbi.nlm.nih.gov/pmc/articles/PMC2814503 $\endgroup$ Commented Feb 14, 2017 at 3:44

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