Can you smash a bacteria (or any microorganism) and kill it? Let's say there is millions of microorganisms on a table. When you put your finger on the table, will or can you kill at least some of them ?
Yes, you can kill bacteria using pressure. The devised used is called a French press
However the pressure use is about 40k psi.... which is a lot higher pressure than anything a human body can generate.
Other methods to kill bacteria include, heat, gamma radiation, oxidative chemicals, antibiotics, dehydration, salt, oxygen exclusion, freezing.
However bacteria are a very diverse group, so it might take one or more methods in combination to kill all bacteria (and their spores) in a sample.