Suppose a naive T cell comes in contact with an APC. How much time does it take for the T Cell to get activated and within how much time does the T cell move away from the APC due to incompatibility in their receptor structure? What is the probability that there will be activation of a naive T cell by an APC (I mean to ask that how many T cells should come in contact with APC before a T cell gets activated, some number like say 1 out of every 1000 t cell gets activated by an APC at a particular time)?

Any resource you can provide that gives a quantitative value of the interaction of T cell with APC, please do if possible.


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