Suppose we have a ribozyme that consists of an 'enzyme' strand and a 'substrate' strand. (e.g. hammerhead ribozyme)

Is it possible to have the enzyme strand of the ribozyme on one RNA molecule and the substrate strand on another RNA molecule (such that it allows multiple-turnover reaction)?

  • $\begingroup$ Are you asking specifically for hammerhead-like ribozymes or would any ribozyme do? The spliceosome, for example, may match your description. $\endgroup$ – canadianer Mar 30 '17 at 18:01

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