While annotating my VCF file with ClinVar, I noted the following value for the
CLNSIG field (i.e., clinical significance):
This is actually reported in this example, so I think the usage of the pipe is quite common for genomic annotations of this kind.
Which is the use of the pipe (
|) character? I looked for it in the VCF file format specification; however, only the meaning of the comma (
,) is specified (i.e., presence of multiple alternate value for that field). I am wondering, instead, what the pipe represents.