We have an assembly of a genome of a Lactobacillus species. The genome also contains a 7.5kb plasmid.
Aside from the "usual plasmid genes" the plasmid contains: - toxin/antitoxin system - Subunit S of type I R/M system (No R or M subunit)
Now, to me this seems like an interesting case. It looks like the plasmid is "exploiting" the R/M system of the host (Bacterium seems to have type I R/M system indeed).
This could have the effect that the plasmid is increasing the fitness of the host (and itself) by making the R/M system more flexible in terms of target sequences by the R/M system (Phages, etc.).
My questions are now:
- Does anyone know an example of such a case. Did not find any.
- Do you think it works the way I suspect.
- Could this be interesting for Biotech applications since phages in diary food environment are a problem.
- How would you test if this plasmid has this effect?